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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3959
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vdr
Name: vitamin D receptor
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdrmultiple interactionsISOVDR (Homo sapiens)6480464CTD[decitabine co-treated with trichostatin A] results in increased expression of VDR mRNA; [decitabine co-treated with trichostatin A] results in increased expression of VDR protein; trichostatin A inhibits the reaction [HR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein]]; trichostatin A inhibits the reaction [HR protein inhibits the reaction [Lithocholic Acid results in increased activity of VDR protein]]; trichostatin A inhibits the reaction [Nickel affects the expression of VDR mRNA]PMID:14575637 PMID:17891453 PMID:22466564
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