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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp53
Name: tumor protein p53
Acc ID: CHEBI:70159
Term: (+)-(S)-ar-turmerone
Definition: A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.
Chemical ID: MESH:C078098
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp53increases expressionISOTP53 (Homo sapiens)6480464CTDar-turmerone results in increased expression of TP53 mRNA; ar-turmerone results in increased expression of TP53 proteinPMID:19250610
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