GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein] | PMID:24451382 PMID:32369900 | | ||||||||||||||||||||||
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