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GENE - TERM ANNOTATION REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: DOID:9005372
Term: Inflammation
Definition: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Definition Source(s): MESH:D007249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TnftreatmentIEP 11059519RGD  
TnftreatmentIEP 11059520RGD  
Tnf ISOTNF (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:11181422 PMID:12843254 PMID:14970111 PMID:16001271 PMID:16227999 PMID:19324842 PMID:19803787 PMID:20167660 PMID:20943792 PMID:21146893 PMID:21467745 PMID:22452660 PMID:23348408 PMID:23371441 PMID:23795810 PMID:34942311
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