GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | increases phosphorylation | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased phosphorylation of STAT3 protein | PMID:31154059 | Stat3 | multiple interactions | ISO | Stat3 (Mus musculus) | 6480464 | CTD | [ITPR3 mutant form results in increased susceptibility to Cadmium] which results in increased expression of STAT3 mRNA; Cadmium promotes the reaction [ITPR3 mutant form results in increased expression of STAT3 mRNA] | PMID:37047547 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Cadmium inhibits the reaction [CNTF protein affects the localization of STAT3 protein]; Cadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein] | PMID:16843830 | | ||||||||||||||||||||||
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