GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | multiple interactions | EXP | | 6480464 | CTD | Dexamethasone inhibits the reaction [Mifepristone results in increased expression of SOD2 mRNA]; Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD2 protein]; Verapamil inhibits the reaction [Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD2 protein]] | PMID:17015168 PMID:9038369 | Sod2 | increases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Dexamethasone results in increased expression of SOD2 mRNA | PMID:19853017 | Sod2 | multiple interactions | ISO | Sod2 (Mus musculus) | 6480464 | CTD | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SOD2 mRNA; Dexamethasone inhibits the reaction [Mercuric Chloride results in increased expression of SOD2 protein] | PMID:16054899 PMID:9374288 | Sod2 | multiple interactions | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | [Dexamethasone co-treated with Bortezomib] inhibits the reaction [IL6 protein results in increased expression of SOD2 mRNA]; [Dexamethasone co-treated with Bortezomib] results in decreased expression of SOD2 mRNA; Dexamethasone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]] | PMID:23063726 PMID:9038369 | |
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