GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | affects expression | EXP | | 6480464 | CTD | Cadmium Chloride affects the expression of SOD2 mRNA | PMID:21442002 | Sod2 | decreases activity | EXP | | 6480464 | CTD | Cadmium Chloride results in decreased activity of SOD2 protein | PMID:12204541 | Sod2 | decreases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in decreased expression of SOD2 mRNA; Cadmium Chloride results in decreased expression of SOD2 protein | PMID:17098586 PMID:21699967 PMID:32392679 | Sod2 | increases acetylation | EXP | | 6480464 | CTD | Cadmium Chloride results in increased acetylation of SOD2 protein | PMID:37451666 | Sod2 | increases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in increased expression of SOD2 mRNA; Cadmium Chloride results in increased expression of SOD2 protein | PMID:20107868 PMID:23099337 PMID:25993096 | Sod2 | multiple interactions | EXP | | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of SOD2 protein; Manganese inhibits the reaction [Cadmium Chloride results in decreased activity of SOD2 protein]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of SOD2 mRNA]; puerarin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of SOD2 protein]; SIRT1 protein inhibits the reaction [Cadmium Chloride results in increased acetylation of SOD2 protein]; SRT1720 inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of SOD2 protein] | PMID:12204541 PMID:32392679 PMID:36527706 PMID:37451666 | Sod2 | decreases activity | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in decreased activity of SOD2 protein | PMID:15964310 | Sod2 | decreases activity | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in decreased activity of SOD2 protein | PMID:27647474 | Sod2 | decreases expression | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in decreased expression of SOD2 mRNA | PMID:11958953 | Sod2 | decreases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in decreased expression of SOD2 protein | PMID:24291162 | Sod2 | increases activity | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased activity of SOD2 protein | PMID:21040778 | Sod2 | increases expression | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in increased expression of SOD2 mRNA | PMID:25528414 | Sod2 | increases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased expression of SOD2 mRNA; Cadmium Chloride results in increased expression of SOD2 protein | PMID:12160620 PMID:24291162 PMID:26525392 | Sod2 | multiple interactions | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SOD2 mRNA | PMID:35301059 | |
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