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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3732
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2
Acc ID: CHEBI:27585
Term: selenomethionine
Definition: A selenoamino acid that is the selenium analogue of methionine.
Chemical ID: MESH:D012645
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2affects response to substanceISOSOD2 (Homo sapiens)6480464CTDSOD2 protein polymorphism affects the susceptibility to Selenomethionine analogPMID:28495429
Sod2increases expressionISOSOD2 (Homo sapiens)6480464CTDSelenomethionine results in increased expression of SOD2 proteinPMID:21215776
Sod2multiple interactionsISOSOD2 (Homo sapiens)6480464CTD[SOD2 protein polymorphism affects the susceptibility to Selenomethionine analog] which affects the expression of CAT mRNA; [SOD2 protein polymorphism affects the susceptibility to Selenomethionine analog] which affects the expression of GPX1 mRNA; [SOD2 protein polymorphism affects the susceptibility to Selenomethionine analog] which affects the expression of SOD1 mRNA; [SOD2 protein polymorphism affects the susceptibility to Selenomethionine analog] which affects the expression of SOD2 mRNAPMID:28495429
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