GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Snca | affects localization | ISO | SNCA (Homo sapiens) | 6480464 | CTD | Iron affects the localization of SNCA protein | PMID:12401952 | Snca | increases response to substance | ISO | SNCA (Homo sapiens) | 6480464 | CTD | SNCA protein mutant form results in increased susceptibility to Iron | PMID:14535945 | Snca | multiple interactions | ISO | SNCA (Homo sapiens) | 6480464 | CTD | Cytarabine promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron]; Hydroxyurea promotes the reaction [SNCA protein mutant form results in increased susceptibility to Iron]; SNCA protein mutant form results in increased susceptibility to [Paraquat co-treated with Iron] | PMID:14535945 PMID:27324791 | Snca | multiple interactions | ISO | Snca (Mus musculus) | 6480464 | CTD | EUK-189 results in decreased susceptibility to [Iron co-treated with Paraquat co-treated with SNCA gene mutant form] | PMID:21039522 | |
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