Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Snca
Name: synuclein alpha
Acc ID: CHEBI:16804
Term: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline
Definition: A benzyltetrahydroisoquinoline that has formula C16H17N.
Chemical ID: MESH:C084924
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sncaincreases expressionISOSNCA (Homo sapiens)6480464CTD1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA mRNA; 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA proteinPMID:15114628
Sncamultiple interactionsISOSNCA (Homo sapiens)6480464CTDacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein]; Acetylcysteine inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein]; coenzyme Q10 inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein]; Selegiline inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein]PMID:15114628
Go Back to source page   Continue to Ontology report