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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3726
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smo
Name: smoothened, frizzled class receptor
Acc ID: CHEBI:80025
Term: Salinomycin
Definition: A spiroketal that has formula C42H70O11.
Chemical ID: MESH:C010327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smodecreases expressionISOSMO (Homo sapiens)6480464CTDsalinomycin results in decreased expression of SMO mRNA; salinomycin results in decreased expression of SMO proteinPMID:25499043 PMID:30273566
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