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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3705
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a2
Name: solute carrier family 2 member 2
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a2increases expressionEXP 6480464CTDGlucose results in increased expression of SLC2A2 mRNAPMID:12787936 PMID:1727734
Slc2a2multiple interactionsEXP 6480464CTDDactinomycin inhibits the reaction [Glucose results in increased expression of SLC2A2 mRNA]; ML 7 inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose]; Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose]PMID:12787936 PMID:17272349
Slc2a2decreases expressionISOSLC2A2 (Homo sapiens)6480464CTDGlucose results in decreased expression of SLC2A2 proteinPMID:24262486
Slc2a2increases expressionISOSlc2a2 (Mus musculus)6480464CTDGlucose results in increased expression of SLC2A2 mRNAPMID:17786952
Slc2a2increases expressionISOSLC2A2 (Homo sapiens)6480464CTDGlucose results in increased expression of SLC2A2 mRNAPMID:36156098
Slc2a2increases transportISOSLC2A2 (Homo sapiens)6480464CTDSLC2A2 protein results in increased transport of GlucosePMID:17710649
Slc2a2multiple interactionsISOSlc2a2 (Mus musculus)6480464CTD[copper bis(3,5-diisopropylsalicylate) co-treated with Glucose] results in increased expression of SLC2A2 protein; [ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein; [Sodium Selenite co-treated with Glucose] results in increased expression of SLC2A2 protein; Glucose inhibits the reaction [Alloxan results in decreased expression of SLC2A2 mRNA]; Glucose results in increased expression of and affects the localization of SLC2A2 proteinPMID:12137914 PMID:12937289 PMID:23795780
Slc2a2multiple interactionsISOSLC2A2 (Homo sapiens)6480464CTDCatechin inhibits the reaction [Glucose results in decreased expression of SLC2A2 protein]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Fructose]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of SLC2A2 protein]PMID:24262486 PMID:8457197
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