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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3705
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a2
Name: solute carrier family 2 member 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SLC2A2 mRNAPMID:22298810
Slc2a2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNAPMID:16054898 PMID:18465118 PMID:18796159 PMID:21215274 PMID:21724226
Slc2a2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC2A2 mRNAPMID:15644576
Slc2a2affects expressionISOSlc2a2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC2A2 mRNAPMID:26377647
Slc2a2affects expressionISOSLC2A2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC2A2 mRNAPMID:22298810
Slc2a2decreases expressionISOSlc2a2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNAPMID:19770486 PMID:27562557
Slc2a2decreases expressionISOSLC2A2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNA; Tetrachlorodibenzodioxin results in decreased expression of SLC2A2 proteinPMID:15056799 PMID:20106945 PMID:21632981 PMID:26159488 PMID:26238291 PMID:31520823
Slc2a2increases expressionISOSlc2a2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC2A2 mRNAPMID:15885268
Slc2a2multiple interactionsISOSlc2a2 (Mus musculus)6480464CTD[Dietary Fats co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLC2A2 mRNAPMID:27713108
Slc2a2multiple interactionsISOSLC2A2 (Homo sapiens)6480464CTD[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SLC2A2 mRNA; AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNA]; ARNT protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNA]; Endosulfan promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [SRC protein results in increased expression of SLC2A2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [ARNT protein results in decreased expression of SLC2A2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Endosulfan results in decreased expression of SLC2A2 mRNA]PMID:26159488 PMID:31520823
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