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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1affects expressionEXP 6480464CTDValproic Acid affects the expression of SLC2A1 proteinPMID:16902764
Slc2a1multiple interactionsEXP 6480464CTD[Valproic Acid co-treated with Lipopolysaccharides] results in decreased expression of SLC2A1 proteinPMID:16902764
Slc2a1decreases expressionISOSLC2A1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of SLC2A1 mRNAPMID:23179753 PMID:27188386
Slc2a1increases expressionISOSLC2A1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of SLC2A1 mRNAPMID:23179753 PMID:24935251 PMID:28001369
Slc2a1multiple interactionsISOSLC2A1 (Homo sapiens)6480464CTDValproic Acid inhibits the reaction [SLC2A1 protein results in increased transport of Glucose]PMID:18455367
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