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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1affects bindingISOSLC2A1 (Homo sapiens)6480464CTDresveratrol binds to SLC2A1 proteinPMID:23615963
Slc2a1decreases expressionISOSlc2a1 (Mus musculus)6480464CTDresveratrol results in decreased expression of SLC2A1 proteinPMID:24221993
Slc2a1multiple interactionsISOSLC2A1 (Homo sapiens)6480464CTD[resveratrol binds to SLC2A1 protein] which results in decreased transport of Hexoses; resveratrol inhibits the reaction [SLC2A1 protein results in increased uptake of Glucose]PMID:23615963
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