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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3696
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc1a1
Name: solute carrier family 1 member 1
Acc ID: CHEBI:32181
Term: tamibarotene
Definition: A dicarboxylic acid monoamide resulting from the condensation of one of the carboxy groups of terephthalic acid with the amino group of 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine.
Chemical ID: MESH:C061133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a1increases activityEXP 6480464CTDtamibarotene results in increased activity of SLC1A1 proteinPMID:19450544
Slc1a1increases expressionEXP 6480464CTDtamibarotene results in increased expression of SLC1A1 proteinPMID:19450544
Slc1a1multiple interactionsEXP 6480464CTDHX 630 promotes the reaction [tamibarotene results in increased activity of SLC1A1 protein]; HX 630 promotes the reaction [tamibarotene results in increased expression of SLC1A1 protein]PMID:19450544
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