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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:43355
Term: indoxyl sulfate
Definition: An aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group.
Chemical ID: MESH:D007200
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expression EXP 401793752RGDindoxyl sulfate increases expression of protein in rat kidney 
Ccl2increases expression ISOCCL2 (Homo sapiens)401793752RGDindoxyl sulfate increases expression of mRNA, protein in HK-2 human kidney proximal tubule cell line 
Ccl2increases expressionISOCCL2 (Homo sapiens)6480464CTDIndican results in increased expression of CCL2 mRNA; Indican results in increased expression of CCL2 proteinPMID:22056374
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