GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | [[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] affects the susceptibility to Ethanol] which results in increased secretion of CCL2 protein; [[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] affects the susceptibility to GHRL protein] which results in increased secretion of CCL2 protein; [Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL2 mRNA; [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL2 mRNA]; [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA; Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CCL2 mRNA]; TNF protein promotes the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CCL2 mRNA] | PMID:16054899 PMID:23503329 PMID:32171850 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of CCL2 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCL2 mRNA | PMID:16997883 PMID:28628672 | | ||||||||||||||||||||||
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