GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine affects the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]] | PMID:10541287 PMID:11124598 PMID:22700867 PMID:26332274 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]] | PMID:18303122 PMID:28555929 PMID:35123994 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL2 mRNA] | PMID:15139008 PMID:17529908 PMID:19158351 PMID:26683377 PMID:33146789 PMID:35065218 | | ||||||||||||||||||||||
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