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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3641
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scnn1g
Name: sodium channel epithelial 1 subunit gamma
Acc ID: CHEBI:26708
Term: sodium atom
Definition: An alkali metal atom that has formula Na.
Chemical ID: MESH:D012964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scnn1gaffects expressionISOScnn1g (Mus musculus)6480464CTDSodium affects the expression of SCNN1G mRNAPMID:15261163
Scnn1gaffects transportISOScnn1g (Mus musculus)6480464CTDSCNN1G protein affects the transport of SodiumPMID:8617496
Scnn1gmultiple interactionsISOSCNN1G (Homo sapiens)6480464CTD[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein binds to SCNN1D protein] which results in increased transport of Sodium; [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which affects the transport of Sodium; [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Sodium; [SCNN1A protein binds to SCNN1B protein mutant form binds to SCNN1G protein] which results in increased transport of Sodium; Amiloride inhibits the reaction [[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Sodium]PMID:18398334 PMID:18665318 PMID:19359370
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