GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3635
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Acc ID: CHEBI:26708
Term: sodium atom
Definition: An alkali metal atom that has formula Na.
CasRN: 7440-23-5
Chemical ID: MESH:D012964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDcyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium]

cypermethrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium]

fenpropathrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium]

fenvalerate affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium]

PMID:18538810
multiple interactionsISORGD:7366016480464CTD[SCN3A protein co-treated with SCN2B protein co-treated with SCN1B protein] results in increased transport of Sodium

2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate inhibits the reaction [[SCN3A protein co-treated with SCN2B protein co-treated with SCN1B protein] results in increased transport of Sodium]

PMID:19026681
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