A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.
Chemical ID:
MESH:C103303
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[9-deoxy-delta-9-prostaglandin D2 co-treated with Alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]
[Alitretinoin co-treated with RXRA protein] results in increased expression of RARB mRNA; Alitretinoin binds to and results in increased activity of RXRA protein; Alitretinoin inhibits the reaction [TGIF1 protein binds to RXRA protein]; Alitretinoin inhibits the reaction [TGIF1 protein results in increased activity of RXRA protein]; Alitretinoin results in increased activity of [RXRA protein binds to NR1I3 protein]; Alitretinoin results in increased activity of [RXRA protein binds to RXRA protein]; ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate inhibits the reaction [Alitretinoin results in increased activity of [RXRA protein binds to RXRA protein]]; RXRA protein promotes the reaction [Alitretinoin results in increased expression of PPARGC1A mRNA]; sodium arsenite inhibits the reaction [[Alitretinoin co-treated with RXRA protein] results in increased expression of RARB mRNA]
1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [Alitretinoin promotes the reaction [[RXRA protein binds to NR1I3 protein] which binds to CYP3A4 promoter]]; [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Alitretinoin] promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]; [Alitretinoin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein; [Alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA protein; [Alitretinoin co-treated with Calcitriol] results in increased stability of [RXRA protein binds to VDR protein]; [Alitretinoin co-treated with RXRA protein] results in increased expression of PSG5 mRNA; [Alitretinoin results in increased activity of RXRA protein] which binds to PSG5 promoter; [pirinixic acid co-treated with Alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA; Alitretinoin analog binds to and results in increased activity of RXRA protein; Alitretinoin binds to and affects the activity of RXRA protein; Alitretinoin binds to and results in increased activity of RXRA protein; Alitretinoin inhibits the reaction [Dimethylformamide results in decreased degradation of RXRA protein]; Alitretinoin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; Alitretinoin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [[RXRA protein binds to NR1I3 protein] which binds to CYP3A4 promoter]]; Alitretinoin promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]; Alitretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Alitretinoin promotes the reaction [[RXRA protein binds to NR1I3 protein] which binds to CYP3A4 promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Alitretinoin results in increased degradation of RXRA protein]; Flurbiprofen inhibits the reaction [Alitretinoin binds to RXRA protein]; RXRA promotes the reaction [Alitretinoin results in increased expression of APOA2 mRNA]; RXRA protein affects the reaction [Alitretinoin results in increased expression of CYP2B6 mRNA]; tributyltin inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenyl bismuth inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenylarsine inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenyltin chloride inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenyltin hydroxide inhibits the reaction [Alitretinoin binds to RXRA protein]
