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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3534
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rara
Name: retinoic acid receptor, alpha
Acc ID: CHEBI:8062
Term: phenethyl caffeate
Definition: An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.
Chemical ID: MESH:C055494
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Raraincreases activityISORARA (Homo sapiens)6480464CTDcaffeic acid phenethyl ester results in increased activity of RARA proteinPMID:16766008
Raraincreases expressionISORARA (Homo sapiens)6480464CTDcaffeic acid phenethyl ester results in increased expression of RARA mRNA; caffeic acid phenethyl ester results in increased expression of RARA proteinPMID:16766008
Raramultiple interactionsISORARA (Homo sapiens)6480464CTD[Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA mRNA; [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA protein; caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased activity of RARA protein]PMID:16766008
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