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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Raf1
Name: Raf-1 proto-oncogene, serine/threonine kinase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Raf1increases expressionEXP 6480464CTDbisphenol A results in increased expression of RAF1 mRNA; bisphenol A results in increased expression of RAF1 proteinPMID:20219716 PMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Raf1increases expressionISORaf1 (Mus musculus)6480464CTDbisphenol A results in increased expression of RAF1 mRNAPMID:33221593
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