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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3407 Species: Rattus norvegicus RGD Object: Gene Symbol: Prlr Name: prolactin receptor

Acc ID: CHEBI:107736 Term: metoclopramide Definition: Metoclopramide is a carboxamide resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine. CasRN: 364-62-5 Chemical ID: MESH:D008787

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:11157	6480464	CTD	Metoclopramide results in increased expression of PRLR mRNA Metoclopramide results in increased expression of PRLR mRNA alternative form	PMID:19304288