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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3395 Species: Rattus norvegicus RGD Object: Gene Symbol: Prkca Name: protein kinase C, alpha

Acc ID: CHEBI:7931 Term: paricalcitol Definition: A seco-cholestane that has formula C27H44O3. CasRN: 131918-61-1 Chemical ID: MESH:C084656

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	paricalcitol inhibits the reaction [Phenylephrine results in increased expression of PRKCA protein modified form] paricalcitol inhibits the reaction [EDN1 protein results in increased expression of PRKCA protein modified form]	PMID:21565836
decreases expression	EXP		6480464	CTD	paricalcitol results in decreased expression of PRKCA protein modified form	PMID:21565836