GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | affects activity | EXP | | 6480464 | CTD | Ibuprofen affects the activity of PPARG protein | PMID:25596134 | Pparg | increases activity | EXP | | 6480464 | CTD | Ibuprofen analog results in increased activity of PPARG protein | PMID:11755111 | Pparg | affects activity | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Ibuprofen affects the activity of PPARG protein | PMID:25596134 | Pparg | increases expression | ISO | Pparg (Mus musculus) | 6480464 | CTD | Ibuprofen results in increased expression of PPARG mRNA | PMID:16407166 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Ibuprofen binds to and results in increased activity of PPARG protein | PMID:9013583 | Pparg | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | Ibuprofen inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of PPARG mRNA]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of PPARG protein] | PMID:16407166 PMID:18946735 | |
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