GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | affects binding | ISO | PPARG (Homo sapiens) | 6480464 | CTD | butylbenzyl phthalate binds to PPARG protein | PMID:23843199 PMID:32407875 | Pparg | increases activity | ISO | PPARG (Homo sapiens) | 6480464 | CTD | butylbenzyl phthalate results in increased activity of PPARG protein | PMID:26172262 | Pparg | increases expression | ISO | Pparg (Mus musculus) | 6480464 | CTD | butylbenzyl phthalate results in increased expression of PPARG mRNA | PMID:27923775 PMID:34520170 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate inhibits the reaction [GW 1929 binds to PPARG protein] | PMID:24155963 PMID:31016361 PMID:33049310 | Pparg | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG protein; butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; PPARG protein promotes the reaction [butylbenzyl phthalate binds to and results in increased activity of PPARG protein] | PMID:24155963 PMID:26820058 PMID:28595985 PMID:33049310 | |
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