GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | affects expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Arsenic affects the expression of PPARG mRNA | PMID:28793237 | Pparg | decreases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Arsenic results in decreased expression of PPARG mRNA; Arsenic results in decreased expression of PPARG protein | PMID:23108036 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of PPARG mRNA; Arsenic inhibits the reaction [CEBPA protein binds to PPARG protein]; Arsenic inhibits the reaction [CEBPB protein binds to PPARG protein]; T 0070907 promotes the reaction [Arsenic results in decreased expression of PPARG protein]; troglitazone inhibits the reaction [Arsenic results in decreased expression of PPARG mRNA]; troglitazone inhibits the reaction [Arsenic results in decreased expression of PPARG protein] | PMID:23108036 PMID:28793237 | | ||||||||||||||||||||||
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