GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | decreases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Amiodarone results in decreased expression of PPARG mRNA | PMID:35641671 | Pparg | increases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Amiodarone results in increased expression of PPARG mRNA | PMID:21123845 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of SCD mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]; Amiodarone binds to and results in increased activity of PPARG protein | PMID:21123845 PMID:24489787 | |
Go Back to source page | Continue to Ontology report |