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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3342
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plat
Name: plasminogen activator, tissue type
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Platincreases expressionEXP 6480464CTDMethamphetamine results in increased expression of PLAT mRNAPMID:19564919
Platmultiple interactionsEXP 6480464CTD[Methamphetamine co-treated with SCH 23390] results in increased expression of PLAT mRNAPMID:19564919
Platincreases expressionISOPlat (Mus musculus)6480464CTDMethamphetamine results in increased expression of PLAT mRNAPMID:15659235
Platmultiple interactionsISOPlat (Mus musculus)6480464CTDRaclopride inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]PMID:15659235
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