GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pdgfrb | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of PDGFRB protein | PMID:17069927 | Pdgfrb | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of PDGFRB mRNA; Carbon Tetrachloride results in increased expression of PDGFRB protein | PMID:15623374 PMID:18006644 PMID:19646978 PMID:24144775 PMID:30783172 | Pdgfrb | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein]; Fish Oils inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein]; olmesartan inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein]; olmesartan inhibits the reaction [Fish Oils inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein]]; Y 27632 inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA] | PMID:18006644 PMID:19646978 PMID:24144775 PMID:30783172 | Pdgfrb | increases expression | ISO | Pdgfrb (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of PDGFRB mRNA; Carbon Tetrachloride results in increased expression of PDGFRB protein | PMID:17962354 PMID:27339419 PMID:27477297 PMID:29987408 PMID:31919559 PMID:34191077 | Pdgfrb | multiple interactions | ISO | Pdgfrb (Mus musculus) | 6480464 | CTD | ESRRG protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; F2R protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; GSK5182 inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein]]; PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB protein] | PMID:17962354 PMID:18038451 PMID:27477297 PMID:34191077 | | ||||||||||||||||||||||
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