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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdgfra
Name: platelet derived growth factor receptor alpha
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgframultiple interactionsEXP 6480464CTDCBL protein affects the reaction [Lead results in decreased expression of PDGFRA protein]; FYN protein affects the reaction [Lead results in decreased expression of PDGFRA protein]; Lead results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of PDGFRA proteinPMID:17298174
Pdgframultiple interactionsISOPDGFRA (Homo sapiens)6480464CTD[lead acetate results in increased abundance of Lead] which results in increased expression of PDGFRA mRNAPMID:32458983
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