GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pcca | decreases expression | ISO | Pcca (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PCCA mRNA | PMID:19770486 PMID:20713471 PMID:21715664 | Pcca | decreases expression | ISO | PCCA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PCCA mRNA | PMID:20064835 PMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424 | Pcca | decreases methylation | ISO | Pcca (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of PCCA exon; Benzo(a)pyrene results in decreased methylation of PCCA intron | PMID:27901495 | Pcca | increases expression | ISO | Pcca (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of PCCA mRNA | PMID:22228805 | Pcca | multiple interactions | ISO | Pcca (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of PCCA mRNA] | PMID:22228805 | |
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