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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3239
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oxtr
Name: oxytocin receptor
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oxtrdecreases expressionISOOxtr (Mus musculus)6480464CTDOzone results in decreased expression of OXTR mRNAPMID:31626304
Oxtrmultiple interactionsISOOxtr (Mus musculus)6480464CTD[[Ozone results in increased oxidation of Particulate Matter] which results in increased chemical synthesis of Aerosols] which results in decreased expression of OXTR mRNA; [[Ozone results in increased oxidation of Vehicle Emissions] which results in increased chemical synthesis of Aerosols] which results in decreased expression of OXTR mRNAPMID:25361045
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