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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Odc1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:82405
Term: Benzoyl peroxide
Definition: A carbonyl compound that has formula C14H10O4.
Chemical ID: MESH:D001585
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Odc1increases activityISOOdc1 (Mus musculus)6480464CTDBenzoyl Peroxide results in increased activity of ODC1 proteinPMID:12065085 PMID:12067571 PMID:12504893 PMID:12804013 PMID:15225900 PMID:15454305 PMID:15629248 PMID:1923905 PMID:2013121 PMID:2105358 PMID:2591024
Odc1increases expressionISOOdc1 (Mus musculus)6480464CTDBenzoyl Peroxide results in increased expression of ODC1 mRNAPMID:15920718
Odc1multiple interactionsISOOdc1 (Mus musculus)6480464CTD2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; allyl sulfide inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; cycloartenol inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron deficiency inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Masoprocol inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Plant Extracts inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]PMID:12065085 PMID:12067571 PMID:12504893 PMID:12804013 PMID:15225900 PMID:15454305 PMID:15629248 PMID:2105358
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