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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3194
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nppb
Name: natriuretic peptide B
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppbincreases expressionEXP 6480464CTDMonocrotaline results in increased expression of NPPB mRNA; Monocrotaline results in increased expression of NPPB proteinPMID:16936438 PMID:36942326
Nppbmultiple interactionsEXP 6480464CTDPropylthiouracil inhibits the reaction [Monocrotaline results in increased expression of NPPB protein]PMID:36942326
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