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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3194 Species: Rattus norvegicus RGD Object: Gene Symbol: Nppb Name: natriuretic peptide B

Acc ID: CHEBI:41977 Term: daunorubicin Definition: A natural product found in Actinomadura roseola. CasRN: 20830-81-3 Chemical ID: MESH:D003630

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Daunorubicin results in decreased expression of NPPB mRNA Daunorubicin results in decreased expression of NPPB protein	PMID:17673002
increases expression	ISO	RGD:69139	6480464	CTD	Daunorubicin results in increased expression of NPPB protein	PMID:11279304