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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3193
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nppa
Name: natriuretic peptide A
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppaincreases expression EXP 401793741RGDsunitinib increases expression of mRNA in rat heart 
Nppaincreases expressionEXP 6480464CTDsunitinib results in increased expression of NPPA mRNAPMID:24247421
Nppamultiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [sunitinib results in increased expression of NPPA mRNA]; SB 203580 promotes the reaction [sunitinib results in increased expression of NPPA mRNA]PMID:24247421
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