GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Notch1 | multiple interactions | ISO | NOTCH1 (Homo sapiens) | 6480464 | CTD | MAPK1 protein promotes the reaction [o,p'-DDT results in increased activity of NOTCH1 protein]; MAPK14 protein promotes the reaction [o,p'-DDT results in increased activity of NOTCH1 protein]; o,p'-DDT results in increased phosphorylation of and results in increased activity of NOTCH1 protein; SB 203580 inhibits the reaction [o,p'-DDT results in increased activity of NOTCH1 protein]; U 0126 inhibits the reaction [o,p'-DDT results in increased activity of NOTCH1 protein] | PMID:18791200 | | ||||||||||||||||||||||
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