GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos3 | decreases expression | EXP | | 6480464 | CTD | carvedilol results in decreased expression of NOS3 mRNA | PMID:16741616 | Nos3 | increases expression | EXP | | 6480464 | CTD | carvedilol results in increased expression of NOS3 mRNA; carvedilol results in increased expression of NOS3 protein | PMID:17559835 PMID:18971572 | Nos3 | increases phosphorylation | EXP | | 6480464 | CTD | carvedilol results in increased phosphorylation of NOS3 protein | PMID:17559835 | Nos3 | multiple interactions | ISO | NOS3 (Homo sapiens) | 6480464 | CTD | Carvedilol inhibits the reaction [Doxorubicin results in decreased phosphorylation of NOS3 protein] | PMID:31066085 | |
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