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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3186
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos3
Name: nitric oxide synthase 3
Acc ID: CHEBI:30879
Term: alcohol
Definition: A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
Chemical ID: MESH:D000438
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos3decreases expressionEXP 6480464CTDAlcohols results in decreased expression of NOS3PMID:24300283
Nos3affects phosphorylationISONOS3 (Homo sapiens)6480464CTDAlcohols affects the phosphorylation of NOS3 proteinPMID:24300283
Nos3decreases expressionISONOS3 (Homo sapiens)6480464CTDAlcohols results in decreased expression of NOS3 proteinPMID:24300283
Nos3multiple interactionsISONOS3 (Homo sapiens)6480464CTDAdenosine Triphosphate affects the reaction [Alcohols affects the phosphorylation of NOS3 protein]; Adenosine Triphosphate inhibits the reaction [Alcohols results in decreased expression of NOS3 protein]PMID:24300283
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