GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos1 | affects response to substance | ISO | Nos1 (Mus musculus) | 6480464 | CTD | NOS1 protein affects the susceptibility to Methamphetamine | PMID:11085313 PMID:11158245 PMID:12050851 PMID:15542708 PMID:20575850 PMID:9495865 | Nos1 | increases expression | ISO | Nos1 (Mus musculus) | 6480464 | CTD | Methamphetamine results in increased expression of NOS1 protein | PMID:10642852 | Nos1 | multiple interactions | ISO | Nos1 (Mus musculus) | 6480464 | CTD | [3-bromo-7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which results in decreased susceptibility to Methamphetamine; [S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Dopamine]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Homovanillic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein] | PMID:11006970 PMID:11085313 PMID:11457507 PMID:17426488 PMID:20575850 PMID:8858965 PMID:9495865 | |
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