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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos1
Name: nitric oxide synthase 1
Acc ID: CHEBI:27086
Term: tributylstannane
Definition: An organotin compound that has formula C12H28Sn.
Chemical ID: MESH:C011559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos1decreases activityEXP 6480464CTDtributyltin results in decreased activity of NOS1 proteinPMID:15464999
Nos1multiple interactionsEXP 6480464CTDCALM1 protein inhibits the reaction [tributyltin results in decreased activity of NOS1 protein]; tributyltin inhibits the reaction [CALM1 protein binds to NOS1 protein]PMID:15464999
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