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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3177
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ngfr
Name: nerve growth factor receptor
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ngfrincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of NGFR mRNA; Acetaminophen results in increased expression of NGFR proteinPMID:17088403 PMID:33387578
Ngfrmultiple interactionsEXP 6480464CTDN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [Acetaminophen results in increased expression of NGFR mRNA]PMID:17088403
Ngfraffects expressionISONgfr (Mus musculus)6480464CTDAcetaminophen affects the expression of NGFR mRNAPMID:17562736
Ngfrincreases expressionISONGFR (Homo sapiens)6480464CTDAcetaminophen results in increased expression of NGFR mRNAPMID:29067470
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