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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3171 Species: Rattus norvegicus RGD Object: Gene Symbol: Nfkbia Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Acc ID: CHEBI:28783 Term: zinc protoporphyrin Definition: A metalloprotoporphyrin that has formula C34H32N4O4Zn. CasRN: 15442-64-5 Chemical ID: MESH:C017803

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735440	6480464	CTD	zinc protoporphyrin inhibits the reaction [cilostazol results in increased expression of NFKBIA protein] zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of NFKBIA protein]	PMID:20131233
multiple interactions	ISO	RGD:10975	6480464	CTD	zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]]	PMID:21925249