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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:17858
Term: glutathione disulfide
Definition: A glutathione derivative that has formula C20H32N6O12S2.
Chemical ID: MESH:D019803
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1increases exportEXP 6480464CTDABCC1 protein results in increased export of Glutathione DisulfidePMID:19053318
Abcc1multiple interactionsEXP 6480464CTD[Epinephrine co-treated with [verlukast results in decreased activity of ABCC1 protein]] results in increased abundance of Glutathione DisulfidePMID:19053318
Abcc1increases activityISOABCC1 (Homo sapiens)6480464CTDGlutathione Disulfide results in increased activity of ABCC1 proteinPMID:11306701
Abcc1increases exportISOABCC1 (Homo sapiens)6480464CTDABCC1 protein results in increased export of Glutathione DisulfidePMID:17272743
Abcc1multiple interactionsISOAbcc1 (Mus musculus)6480464CTDABCC1 protein affects the reaction [AGT protein results in decreased abundance of Glutathione Disulfide]PMID:17272743
Abcc1multiple interactionsISOABCC1 (Homo sapiens)6480464CTDGlutathione Disulfide inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; Glutathione Disulfide promotes the reaction [Leukotriene C4 analog binds to ABCC1 protein]PMID:15628876 PMID:21918036
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