GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk3 | affects expression | EXP | | 6480464 | CTD | Dieldrin affects the expression of MAPK3 mRNA | PMID:22546817 | Mapk3 | increases phosphorylation | EXP | | 6480464 | CTD | Dieldrin results in increased phosphorylation of MAPK3 protein | PMID:15531431 PMID:18040759 PMID:35137321 | Mapk3 | multiple interactions | EXP | | 6480464 | CTD | Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK3 protein] | PMID:35137321 | Mapk3 | increases phosphorylation | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | Dieldrin results in increased phosphorylation of MAPK3 protein | PMID:21278053 | Mapk3 | multiple interactions | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK3 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] | PMID:15888667 | Mapk3 | multiple interactions | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] | PMID:21278053 | | ||||||||||||||||||||||
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