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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:31206
Term: ammonium chloride
Definition: An inorganic chloride having ammonium as the counterion.
Chemical ID: MESH:D000643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3affects expressionEXP 6480464CTDAmmonium Chloride affects the expression of MAPK3 mRNAPMID:16483693
Mapk3increases expressionEXP 6480464CTDAmmonium Chloride results in increased expression of MAPK3 proteinPMID:16483693
Mapk3increases phosphorylationEXP 6480464CTDAmmonium Chloride results in increased phosphorylation of MAPK3 proteinPMID:11923223
Mapk3multiple interactionsEXP 6480464CTDDizocilpine Maleate inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK3 protein]; Uric Acid inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK3 protein]PMID:11923223
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