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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3multiple interactionsEXP 6480464CTDGallic Acid inhibits the reaction [ALB modified form results in increased phosphorylation of MAPK3 protein]PMID:24309158
Mapk3decreases expressionISOMAPK3 (Homo sapiens)6480464CTDGallic Acid results in decreased expression of MAPK3 protein modified formPMID:22387266
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTDGallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; SRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]PMID:27087131
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